Prostate Cancer Screenings: Early Detection Improves Outcomes
Courtney Carter
/ Categories: WELLNESS, 2024

Prostate Cancer Screenings: Early Detection Improves Outcomes

In the United States, 1 in 8 men will be diagnosed with prostate cancer in his lifetime. Despite the alarmingly high number of men who develop prostate cancer, there is good news: more than 80% of all prostate cancers are detected when the cancer is confined to the prostate or the region around it, making it highly treatable. In fact, the 5-year survival rate in the U.S. for men diagnosed with early-stage prostate cancer is greater than 99%.

However, that success rate doesn’t mean prostate cancer is never deadly. Every day, 94 men die from prostate cancer in the U.S., making it the second leading cause of cancer death among men in the country. The real tragedy in those numbers is how easy it is to screen for the disease.

The most common screening method is a simple blood test called prostate specific antigen (PSA).

PSA is a substance made by the prostate, which then becomes detectable in your blood. PSA levels tend to be higher in men who have prostate cancer. But because other factors can influence PSA levels, including age, benign prostate enlargement, and certain medications, it’s important to let your doctor interpret your PSA test results. If your levels are abnormal, your doctor may refer you to a urologist who may recommend other tests, including imaging or prostate biopsy. It’s important to note that the actual diagnosis of prostate cancer can only be made with a biopsy.

 

As for who should get a screening and when, the American Cancer Society recommends men discuss screening with their doctor at the following ages and risk levels:

  • Age 40 for men at even higher risk (those with more than one first-degree relative who had prostate cancer at an early age)

  • Age 45 for men at high risk of developing prostate cancer. This includes African American men and men who have a first-degree relative (father or brother) diagnosed with prostate cancer at an early age (younger than age 65).

  • Age 50 for men who are at average risk of prostate cancer and are expected to live at least 10 more years

If no prostate cancer is found, the timing for future screenings will be determined by the findings of the PSA test:

  • Men who have a PSA level of less than 2.5 ng/mL may only need to be retested every 2 years.

  • Screening should be done yearly for men whose PSA level is 2.5 ng/mL or higher.

 

WHEN TO SEE A DOCTOR

In most cases, early prostate cancer has very few or no symptoms. When they do appear, they may include:

  • Problems urinating, including a slow or weak urinary stream, or the need to urinate more often

  • Blood in the urine or semen

Symptoms of more advanced prostate cancer can include those noted above and:

  • Trouble getting an erection (erectile dysfunction or ED)

  • Pain in the hips, back (spine), chest (ribs), or other areas, from cancer that has spread to the bones

  • Weakness or numbness in the legs or feet, or even loss of bladder or bowel control, from cancer in the spine pressing on the spinal cord

  • Weight loss

  • Feeling very tired

In many cases, these symptoms are caused by something other than prostate cancer. However, it’s still important to tell your health care provider about your symptoms so they can determine the cause and treat it.

 

Matthew Vernon, MD, is a radiation oncologist at the Dartmouth Regional Cancer Center at Southwestern Vermont Medical Center 

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Moving Forward Safely

One of the most frustrating and anxiety-producing traits of our COVID –19 pandemic is how much uncertainty is involved in all aspects of this disease. Symptoms caused by the Coronavirus, age groups affected, the usefulness of medications, anticipated death rate, and the timeline for development of a vaccine are examples of information that sometimes change on a weekly basis.

Vermonters have done a great job of limiting the spread of the virus and protecting our most vulnerable neighbors by following the Governor's "Stay Home, Stay Safe" order over the past few months. Now, we've all been directed to wear masks in public. Both Bennington and Wilmington's Select Boards have passed local mandates requiring masks in public places. Thanks to these efforts—along with distancing, handwashing, and other factors—Vermont is among the states with the fewest number of infections. Continuing each of these important infection-prevention strategies is crucial to returning to a more normal way of life.

As we open up and begin to re-connect, we fully expect to see a rise in COVID –19 cases in Vermont. Thankfully, we have had time to prepare for this increase. We also have adequate PPE, and increased testing will help us gather crucial information for stemming the spread with less disruption to our normal lives.

More than ever, I find it helpful to focus on what we have learned and how it can help us move forward safely. Here is some of what we have learned so far: Most large hospitals, often treating over 1000 COVID patients daily, effectively protected their workers by obsessively following the rules of screening, hygiene, distancing, and masking. Each of these components is designed to work together; Each alone has its inherent limits.

  • Absent quick testing at the workplace, the best screening is asking employees if they have COVID-like symptoms (fever, chills, new cough, shortness of breath, sore throat, loss of taste or smell) and to stay home if they do.
  • Washing our hands (or using sanitizer) after touching well-handled items or visiting populated areas. Washing your hands 10 times daily is not too often.
  • Though an uncovered sneeze or cough can travel farther, 6 feet distancing continues to be the sweet spot for safety.
  • Masks (double layer cotton and surgical) are effective to prevent spreading of large and some small droplets containing virus. They also seem to give some minimal protection to those wearing a mask. Since possibly 40 percent of transmission happens when we do not have symptoms, we wear our masks to protect others and to suppress overall infection rate. They also help many people (not all) to avoid touching their face. The downside is a warm chin; the upside is you may be protecting someone from a significant illness. Masks are not a symbol of government intrusion. Masks are simply a tool to protect others and show empathy.

It is difficult to predict how many COVID-19 infections will occur in our communities in the coming months. What I am certain of is that our choices, on where we go and what we do, often affect the safety of those around us. As we learn to live with this virus in our community, following the recommendation above will help us all.

Marie George, MD, is SVMC’s infectious disease specialist.

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