Medical Matters Weekly Welcomes Leading Pediatric Cancer Researcher
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Medical Matters Weekly Welcomes Leading Pediatric Cancer Researcher

BENNINGTON, VT—October 11, 2022—The next guest on Medical Matters Weekly is Mariella Filbin, MD, PhD, a leading researcher working to find a cure to children’s brain tumors. The show airs on Facebook Live at 12 p.m. on Wednesday, October 19.

The show is produced by Southwestern Vermont Health Care (SVHC) with cooperation from Catamount Access Television (CAT-TV). Viewers can view on facebook.com/svmedicalcenter and facebook.com/CATTVBennington. The show is also available to view or download as a podcast on svhealthcare.org/medicalmatters.

Dr. Filbin is the co-director for Research for the Pediatric-Neurooncology Program at Dana-Farber Cancer Institute and Boston Children’s Hospital. She earned her doctoral degrees in biochemistry and molecular biology from the Medical University of Graz, Austria. After a pediatric residency at Boston Children’s Hospital, she completed a fellowship in pediatric hematology/oncology at the Dana-Farber/Boston Children’s Cancer and Blood Disorders Center. She joined the faculty at Dana-Farber/Boston Children's as a pediatric neuro-oncologist in July 2017. In addition to her role in the treatment of patients with brain tumors, her research focuses on establishing cellular networks of tumor dependencies in pediatric brain tumors with the goal of finding new targeted therapies.

The Filbin Lab at the Dana-Farber Cancer Institute studies pediatric brain tumors, particularly the lethal high-grade gliomas, including DIPG and malignant embryonal brain tumors that are in greatest need of therapeutic improvements. The team is especially interested in how the specific developmental and cellular contexts in which tumorigenic mutations arise shape the cellular hierarchy of the resulting tumors. They combine single-cell genetics and transcriptomics with gene editing, epigenetic, stem cell and pharmacologic methods to identify these cellular states, hierarchies and networks underlying tumorigenesis, with the goal of establishing new druggable targets.

The show is broadcast on Facebook Live, YouTube, and all podcast platforms. After the program, the video is available on area public access television stations CAT-TV (Comcast channel 1075) and GNAT-TV's (Comcast channel 1074), as well as on public access stations throughout the United States.

About SVHC:
Southwestern Vermont Health Care (SVHC) is a comprehensive, preeminent, healthcare system providing exceptional, convenient, and affordable care to the communities of Bennington and Windham Counties of Vermont, eastern Rensselaer and Washington Counties of New York, and northern Berkshire County in Massachusetts. SVHC includes Southwestern Vermont Medical Center (SVMC), Southwestern Vermont Regional Cancer Center, the Centers for Living and Rehabilitation, and the SVHC Foundation. SVMC includes 25 primary and specialty care practices.

Southwestern Vermont Health Care is among the most lauded small rural health systems in the nation. It is the recipient of the American Hospital Association’s 2020 Rural Hospital Leadership Award. In addition, SVMC ranked fourth nationwide for the value of care it provides by the Lown Institute Hospital Index in 2020 and is a five-time recipient of the American Nurses Credentialing Center’s Magnet® recognition for nursing excellence. The health system is fortunate to have the support of platinum-level corporate sponsor Mack, a leading supplier of contract manufacturing services and injection molded plastic parts based in Arlington, VT.

Southwestern Vermont Medical Center provides exceptional care without discriminating on the basis of an individual’s age, race, ethnicity, religion, culture, language, physical or mental disability, socioeconomic status, sex, sexual orientation, or gender identity or expression. Language assistance services, free of charge, are available at 1-800-367-9559.

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5 Questions with the Chair of the Department of Surgery

Malcolm Paine, MD, of SVMC OB/GYN, serves as the chair of the Department of Surgery. We asked him five questions about COVID-19 and how it feels to deliver care right now.

SVMC: What would you like to share with patients at this time?
MP: First, on behalf of the Department of Surgery, I would like to acknowledge how tough it has been for our community members who have been affected by this pandemic. We see such tremendous strength in those who have been ill or lost loved ones to illness and in those who are working hard to get by without a job or while homeschooling their children. We are proud to be part of this community, whose careful social distancing efforts have prevented an unmanageable surge.

We are grateful, too, that as restrictions loosen, we can get back to seeing patients and providing care in a timely way. On the surface, the care may look or feel a little different—everyone will be wearing masks, for instance—but once we get accustomed to the changes, we hope that you will recognize the same level of personalized care we all enjoyed before COVID-19.

SVMC: What are the potential risks associated with postponing care?
MP: There are many types of surgery that can be delayed for a short time, often without any negative repercussions . However, surgery is often for situations that cause pain, and delaying the procedure can result in that pain getting worse or not getting better. Sometimes, there are situations where a minor surgery, if delayed, can turn into a more major or emergency surgery, and the patient can become very sick.

SVMC: In general, what additional precautions have been put in place to ensure that care is safe?
MP: We are absolutely committed to the safety of our patients, staff, and the community. We know how important it is for patients to be able to know and trust that we have their safety in mind at all times. We always want to use the best science and advice from the State to guide our practices. We have put several new measures in place.

We screen all patients and advocates who come to the hospital to make sure they do not have a fever or possible symptoms of COVID-19. All staff also undergo daily screening for fever and symptoms to make sure those looking after patients are healthy. We are also testing all patients with planned surgical procedures for COVID-19. This is performed as an outpatient test at no cost to the patient and increases our confidence that we are not putting patients or staff at increased risk. Patients with a scheduled surgery are encouraged to call ahead if they are feeling unwell, and after surgery, patients will be asked to check for fever for 14 days to make sure they stay healthy.

SVMC: How would patients be notified if COVID risk increased rapidly?
MP: There is always the chance that there may be a new "surge." In that case, a directive to stop elective procedures would likely come from the State. We may also decide, as a hospital, to stop these procedures in order to keep everyone safe. In that case, we would call the patients to let them know that their scheduled case is delayed until the risk decreases.

SVMC: How would you estimate the risk of contracting COVID-19 at the hospital right now?
MP: We are tracking these numbers on a daily basis. With all of these safety measures in place and due to the very low numbers of cases we are seeing in this area at the present time, we estimate this risk is extremely low.

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