Medical Matters Weekly Welcomes Leading Pediatric Cancer Researcher
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Medical Matters Weekly Welcomes Leading Pediatric Cancer Researcher

BENNINGTON, VT—October 11, 2022—The next guest on Medical Matters Weekly is Mariella Filbin, MD, PhD, a leading researcher working to find a cure to children’s brain tumors. The show airs on Facebook Live at 12 p.m. on Wednesday, October 19.

The show is produced by Southwestern Vermont Health Care (SVHC) with cooperation from Catamount Access Television (CAT-TV). Viewers can view on facebook.com/svmedicalcenter and facebook.com/CATTVBennington. The show is also available to view or download as a podcast on svhealthcare.org/medicalmatters.

Dr. Filbin is the co-director for Research for the Pediatric-Neurooncology Program at Dana-Farber Cancer Institute and Boston Children’s Hospital. She earned her doctoral degrees in biochemistry and molecular biology from the Medical University of Graz, Austria. After a pediatric residency at Boston Children’s Hospital, she completed a fellowship in pediatric hematology/oncology at the Dana-Farber/Boston Children’s Cancer and Blood Disorders Center. She joined the faculty at Dana-Farber/Boston Children's as a pediatric neuro-oncologist in July 2017. In addition to her role in the treatment of patients with brain tumors, her research focuses on establishing cellular networks of tumor dependencies in pediatric brain tumors with the goal of finding new targeted therapies.

The Filbin Lab at the Dana-Farber Cancer Institute studies pediatric brain tumors, particularly the lethal high-grade gliomas, including DIPG and malignant embryonal brain tumors that are in greatest need of therapeutic improvements. The team is especially interested in how the specific developmental and cellular contexts in which tumorigenic mutations arise shape the cellular hierarchy of the resulting tumors. They combine single-cell genetics and transcriptomics with gene editing, epigenetic, stem cell and pharmacologic methods to identify these cellular states, hierarchies and networks underlying tumorigenesis, with the goal of establishing new druggable targets.

The show is broadcast on Facebook Live, YouTube, and all podcast platforms. After the program, the video is available on area public access television stations CAT-TV (Comcast channel 1075) and GNAT-TV's (Comcast channel 1074), as well as on public access stations throughout the United States.

About SVHC:
Southwestern Vermont Health Care (SVHC) is a comprehensive, preeminent, healthcare system providing exceptional, convenient, and affordable care to the communities of Bennington and Windham Counties of Vermont, eastern Rensselaer and Washington Counties of New York, and northern Berkshire County in Massachusetts. SVHC includes Southwestern Vermont Medical Center (SVMC), Southwestern Vermont Regional Cancer Center, the Centers for Living and Rehabilitation, and the SVHC Foundation. SVMC includes 25 primary and specialty care practices.

Southwestern Vermont Health Care is among the most lauded small rural health systems in the nation. It is the recipient of the American Hospital Association’s 2020 Rural Hospital Leadership Award. In addition, SVMC ranked fourth nationwide for the value of care it provides by the Lown Institute Hospital Index in 2020 and is a five-time recipient of the American Nurses Credentialing Center’s Magnet® recognition for nursing excellence. The health system is fortunate to have the support of platinum-level corporate sponsor Mack, a leading supplier of contract manufacturing services and injection molded plastic parts based in Arlington, VT.

Southwestern Vermont Medical Center provides exceptional care without discriminating on the basis of an individual’s age, race, ethnicity, religion, culture, language, physical or mental disability, socioeconomic status, sex, sexual orientation, or gender identity or expression. Language assistance services, free of charge, are available at 1-800-367-9559.

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Introducing Dr. Amy Freeth

Amy E. Freeth, MD, resumed endocrinology services at SVMC in March 2020. The practice, known as SVMC Endocrinology, is a part of Southwestern Vermont Medical Center (SVMC) and Southwestern Vermont Health Care (SVHC). It replaces the Bennington Osteoporosis Center, where Dr. David Gorson had provided similar services to the community until his retirement in 2019.

How do you describe endocrinology to people who don’t know what it is? The endocrine system is made up of glands that make hormones. These hormones are chemical messengers that travel via the bloodstream to communicate with the cells and organs of the body. Hormones are important for growth, development, mood, metabolism, and reproduction. These glands include the pituitary, thyroid, parathyroid, pancreas, adrenal, testes, and ovaries.

Endocrinology is a practice of medicine that specializes in disorders of these systems. Disorders most commonly are related to underactive or overactive function of these glands and require replacement of the hormone or specific treatments such as medications, ablation, or surgery.

Since hormones function in feedback loops and are part of a larger complex functional system that exists in flow with the human body, replacement hormones or treatment of endocrine disorders can be challenging and involve changes to our lifestyles that support the optimal functioning of the body.

What diagnoses are most common among the patients you treat?  Pituitary tumors, hypothyroidism, hyperthyroidism, thyroid nodules, thyroid cancer, hyperparathyroidism, osteoporosis, diabetes, adrenal insufficiency, Cushing’s disease, primary hyperaldosteronism, pheochromocytoma, obesity, and polycystic ovarian syndrome.

What sorts of treatments do you offer? I offer comprehensive consultation and management of endocrine disorders. I also interpret testing and make treatment plans for endocrine disorders. I also provide interpretation of bone density reports and perform fine needle aspiration biopsies in collaboration with Radiology Associates of Bennington. Technology is increasingly becoming more important in the management of diabetes. Technology includes glucose meters, insulin pumps, and continuous glucose monitoring (sensors). I work with certified diabetes educators to create a team approach to diabetes management. As we develop this new department, we are looking for innovative ways to help people regain and optimize their health. I have training in nutrition counseling and health coaching to help people find their path to good health.

Why is it important for patients who need an endocrinologist see them regularly? Your endocrinologist is part of your health team and has experience and a deep understanding of what is happening within your body to help assess, guide, and co-manage your disorder. There is testing that may need to be done to make sure you are living with optimal hormonal balance. Allowing hormones to run too low or too high can have lasting adverse effects on the body leading to other disease or imbalances.

How do you help protect patients who need to come into the office from infections, like COVID-19? At this time, I am seeing patients via telemedicine and phone visits. This week we are starting to see a portion of our patients in the clinic. Patients can register on the phone and wait in their car until the room is ready. Patients will be screened for fever and should wear a mask. Staff will wear proper protective equipment and follow guidelines for handwashing and cleaning of the rooms.

Since many patients who will likely want to come to the endocrinology clinic will be members of high-risk populations (diabetes, hypertension, obesity, and the elderly), patients will have a choice of the type of visit they have.

Dr. Freeth sees patients 8 a.m. – 5 p.m. Tuesday - Thursday in Suite 307 of the Medical Office Building located at 140 Hospital Drive in Bennington. For an appointment, call 802-447-4555. The schedule will expand to additional days as needed.

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