Medical Matters Weekly Welcomes Leading Pediatric Cancer Researcher
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Medical Matters Weekly Welcomes Leading Pediatric Cancer Researcher

BENNINGTON, VT—October 11, 2022—The next guest on Medical Matters Weekly is Mariella Filbin, MD, PhD, a leading researcher working to find a cure to children’s brain tumors. The show airs on Facebook Live at 12 p.m. on Wednesday, October 19.

The show is produced by Southwestern Vermont Health Care (SVHC) with cooperation from Catamount Access Television (CAT-TV). Viewers can view on facebook.com/svmedicalcenter and facebook.com/CATTVBennington. The show is also available to view or download as a podcast on svhealthcare.org/medicalmatters.

Dr. Filbin is the co-director for Research for the Pediatric-Neurooncology Program at Dana-Farber Cancer Institute and Boston Children’s Hospital. She earned her doctoral degrees in biochemistry and molecular biology from the Medical University of Graz, Austria. After a pediatric residency at Boston Children’s Hospital, she completed a fellowship in pediatric hematology/oncology at the Dana-Farber/Boston Children’s Cancer and Blood Disorders Center. She joined the faculty at Dana-Farber/Boston Children's as a pediatric neuro-oncologist in July 2017. In addition to her role in the treatment of patients with brain tumors, her research focuses on establishing cellular networks of tumor dependencies in pediatric brain tumors with the goal of finding new targeted therapies.

The Filbin Lab at the Dana-Farber Cancer Institute studies pediatric brain tumors, particularly the lethal high-grade gliomas, including DIPG and malignant embryonal brain tumors that are in greatest need of therapeutic improvements. The team is especially interested in how the specific developmental and cellular contexts in which tumorigenic mutations arise shape the cellular hierarchy of the resulting tumors. They combine single-cell genetics and transcriptomics with gene editing, epigenetic, stem cell and pharmacologic methods to identify these cellular states, hierarchies and networks underlying tumorigenesis, with the goal of establishing new druggable targets.

The show is broadcast on Facebook Live, YouTube, and all podcast platforms. After the program, the video is available on area public access television stations CAT-TV (Comcast channel 1075) and GNAT-TV's (Comcast channel 1074), as well as on public access stations throughout the United States.

About SVHC:
Southwestern Vermont Health Care (SVHC) is a comprehensive, preeminent, healthcare system providing exceptional, convenient, and affordable care to the communities of Bennington and Windham Counties of Vermont, eastern Rensselaer and Washington Counties of New York, and northern Berkshire County in Massachusetts. SVHC includes Southwestern Vermont Medical Center (SVMC), Southwestern Vermont Regional Cancer Center, the Centers for Living and Rehabilitation, and the SVHC Foundation. SVMC includes 25 primary and specialty care practices.

Southwestern Vermont Health Care is among the most lauded small rural health systems in the nation. It is the recipient of the American Hospital Association’s 2020 Rural Hospital Leadership Award. In addition, SVMC ranked fourth nationwide for the value of care it provides by the Lown Institute Hospital Index in 2020 and is a five-time recipient of the American Nurses Credentialing Center’s Magnet® recognition for nursing excellence. The health system is fortunate to have the support of platinum-level corporate sponsor Mack, a leading supplier of contract manufacturing services and injection molded plastic parts based in Arlington, VT.

Southwestern Vermont Medical Center provides exceptional care without discriminating on the basis of an individual’s age, race, ethnicity, religion, culture, language, physical or mental disability, socioeconomic status, sex, sexual orientation, or gender identity or expression. Language assistance services, free of charge, are available at 1-800-367-9559.

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Interview with Jeff Silverman: 3D Printer

Jeff Silverman is a Wilmington native, a volunteer firefighter, and a business owner. From an addition to his Whitingham, Vermont, farm house, his company, Inertia Unlimited, develops camera technology for broadcast television.

"We make them out of thin air," he says.

Actually, he uses a 3D printer to make prototypes and one-of-a-kind cameras for very specific purposes, including those that sit in the dirt in front of a batter during Major League Baseball games and the ones built into NASCAR racetracks.

Over the course of the COVID-19 pandemic, Jeff has printed 463 face shields for first responders in the Deerfield Valley and healthcare workers at Southwestern Vermont Medical Center and other places. He has delivered them free of charge.

When and how did you first become interested in printing shields for first responders? In one day, every job we had disappeared. We went from having 20 – 30 jobs to zero in one day. Our first thought was that we would use the materials and talent we typically use to sew the pouches for our cameras to make masks. But we quickly found that the proper materials and techniques were not available to make effective masks. Plus so many other people were making them. They had it covered.

On Sunday, March 22, I read in the New York Times that a company in Syracuse, NY, had made a design to 3D print face shields available online. By noon that day I was printing. Since then the printer has not stopped.

How does it work? The printer converts the design into a 3D object using filament that is the width of a human hair, adding layer by layer. The printer takes 2 hours to print one shield. I have produced 380 shields so far. That's 1000 hours of printing. I take from midnight to 5 a.m. off. We've done more 3D printing in the last month and a half than we had in the previous 5 years.

Describe the shields. It was important to me to produce something that was good quality. Sometimes the ones you buy don’t clean up very well. These can survive UV light and other sterilization. They are rough and tough.

Where have you distributed them? First I gave them to the firefighters in Wilmington and Whitingham, where I am a volunteer. Then I gave some to the Deerfield Valley Rescue. I have sent 324 to Southwestern Vermont Health Care, some to SVMC Deerfield Valley Campus; Golden Cross Ambulance Service and Sojourns Community Clinic, both in Westminster, VT; and Rescue Inc. in Brattleboro. I sent some to a dentist in Portland, ME, who asked, and 10 to North Central Bronx Hospital to a friend who works there.

What's your greatest accomplishment? I went to Wilmington High School in the late 70s, and Dave Larson, who was the social studies teacher and former longtime VT state representative, had a video camera. He let me borrow it to film field hockey games. At the end of the season, they gave me a varsity letter for my film work. I have won Emmys since, but that varsity letter is special, because it represented the beginning.

What's next? We look forward to reopening. For us, it's the easiest thing in the world. No client ever comes here. We didn't lay anybody off. We hired locals. All are full-time with benefits. We think Vermont is a great place for low-impact companies like ours, and we hope more companies discover Vermont and come here to provide well-paid jobs.

And I am really looking forward to turning the printer off.

On behalf of Southwestern Vermont Health Care's frontline staff, thank you to Jeff for his tireless efforts to provide vital equipment to our teams. We appreciate it!

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